Lobelia inflata, also known as Indian-tobacco or puke weed, is an annual or biennial herbaceous plant native to eastern North America. Growing up to 100cm tall, its violet flowers bloom from mid-summer to fall. This plant has a long history of use in traditional medicine by indigenous peoples for respiratory and muscle disorders, as a purgative, and as a ceremonial medicine. Its leaves contain 52 different alkaloid compounds, the most studied being lobeline. Nowadays, it is mainly used as a powerful antispasmodic herb in the treatment of respiratory and muscle disorders. However, caution must be taken as excessive doses can cause adverse effects including nausea, rapid heartbeat, tremors, and possibly death. This plant can be propagated by seed and is suitable for light, medium, and heavy soils. It prefers moist soil and can grow in semi-shade or no shade.