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Sambucus williamsii North China Red Elder is a deciduous shrub that has been shown to have remarkable health benefits. Studies have demonstrated that the 60% ethanol crude extract of this plant improved bone mass, strength, and micro-structure in both mice and rats. The present study aims to identify the bioactive fractions and ingredients responsible for these effects. The plant has several traditional medicinal uses, and its different parts are known to treat various ailments. The flowers are diaphoretic and diuretic, while the leaf serves to break ague fits. The juice of the stem is emetic, and a decoction of the root is used to treat rheumatoid arthritis. Recent research has identified SWC as the most potent fraction in stimulating cell proliferation and differentiation and restoring bone mineral density. Lignans were identified as the potential bioactive components responsible for these effects. Sambucus williamsii North China Red Elder prefers moist soil and can grow in light woodland or no shade. It can tolerate atmospheric pollution and strong winds but not maritime exposure. Get the unparalleled health benefits of Sambucus williamsii North China Red Elder today.